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To many, genomics is merely exploitable technology for the leviathan of biotechnology. This is both shallow and short sighted. Genomics is applied knowledge based on profound and evolving science about how living things develop, how healthy or sick we are, and what our future will be like. In health care, genomics technologies are disruptive yet potentially cost-effective because they enable primary prevention, the antidote to runaway costs and declining productivity. The challenges to integration are great, however, and many bioethical and social-policy implications are alarming. Because it is poorly understood today, we must debate genomics vigorously if we are to act wisely. Public policy must lead.
Abernethy, B. 2000. Transcript: Bob Abernethy's Interview with Dr. Francis Collins, Director of the Human Genome Project at the National Institutes of Health. June 16. Religion and Ethics Newsweekly. www.pbs.org/wnet/religionandethics/transcripts/collins.html (accessed August 7, 2007).
Anderson, G. F. 1986. National Medical Care Spending. Health Affairs 5 (3): 123-130.[CrossRef][Medline]
Brown, L. 1982. Politics and Health Care Organizations: Health Maintenance Organizations as Federal Policy. Washington, DC: Brookings Institution.
Centers for Medicare and Medicaid Services (CMS). 2006. National Health Expenditure Projections 2006–2016: Forecast Summary. www.cms.hhs.gov/NationalHealthExpendData/downloads/proj2006.pdf (accessed August 7, 2007).
Christensen, C. M., R. Bohmer, and J. Kenagy. 2000. Will Disruptive Innovations Cure Health Care? Harvard Business Review 78 (5): 102-112.[Web of Science][Medline]
Clarke, A. C. 1951. The Exploration of Space. New York: Harper.
———. 1962. Profiles of the Future. New York: Harper and Row.
Fuhrmans, V. 2006. Unstable Condition: After Streak of Strong Profits, Health Insurers May See Decline. Wall Street Journal, July 31.
GenBank National Center for Biotechnology Information. 2007. Trace Archive. www.ncbi.nlm.nih.gov/Traces/trace.cgi (accessed October 20, 2007).
Kohane, I. S., D. R. Masys, and R. B. Altman. 2006. The Incidentalome: A Threat to Genomic Medicine. Journal of the American Medical Association 296: 212-215.
Levy, S., G. Sutton, P. C. Ng, L. Feuk, A. L. Halpern, B. P. Walenz, N. Axelrod, et al. 2007. The Diploid Genome Sequence of an Individual Human. PLoS Biology 5: e254. dx.doi.org/10.1371%2Fjournal.pbio.0050254 (accessed October 20, 2007).[CrossRef][Medline]
President's Commission on Bioethics. 2003. Beyond Therapy: Biotechnology and the Pursuit of Happiness. Washington, DC: U.S. Government Printing Office.
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